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The aim of this study is to examine the effects of the earthquake on the psychological symptoms of high school students, and to understand the readiness of school counseling services based on the available data. In this context, the research was designed within the scope of two different studies: Study 1: The views of school counselors, and students on the difficulties experienced due to the earthquake. Study 2: The effects of the earthquake on students' psychological symptoms.

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Behavioral and neurophysiological effects of electrical stunning on zebrafish larvae.

Lab Anim (NY)

January 2025

Werner Reichardt Centre for Integrative Neuroscience and Institute for Neurobiology, University of Tuebingen, Tuebingen, Germany.

Two methods dominate the way that zebrafish larvae are euthanized after experimental procedures: anesthetic overdose and rapid cooling. Although MS-222 is easy to apply, this anesthetic takes about a minute to act and fish show aversive reactions and interindividual differences, limiting its reliability. Rapid cooling kills larvae after several hours and is not listed as an approved method in the relevant European Union directive.

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Increasing variability down serially segmented structures, such as mammalian molar teeth and vertebrate limb segments, is a much-replicated pattern. The same phenotypic pattern has conflicting interpretations at different evolutionary scales. Macroevolutionary patterns are thought to reflect greater evolutionary potential in later-forming segments, but microevolutionary patterns are thought to reflect less evolutionary potential and greater phenotypic plasticity.

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Durable T cell immunity against cancer depends on the continual replenishment of effector CD8+ T cells. Thymic output has been correlated with favorable prognosis in cancer patients across a range of ages, suggesting that the thymus is an important source for replenishing T cells capable of controlling cancer progression. However, the effector potential of thymic mature CD8+ T cells and their regulation have not been clearly defined.

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Knowledge of the natural history of deficiency disorder (CDD) is limited to the results of cross-sectional analysis of largely pediatric cohorts. Assessment of outcomes in adulthood is critical for clinical decision-making and future precision medicine approaches but is challenging because of the diagnostic gap and duration of follow-up that would be required for prospective studies. We aimed to delineate the natural history retrospectively from adulthood.

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