Fatal calciphylaxis in two patients with giant cell arteritis.

Clin Rheumatol

Department of General Internal Medicine, University Hospital Gasthuisberg, Dienst Algemene Inwendige Geneeskunde, UZ Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.

Published: May 2007

Two elderly female patients with fatal calciphylaxis, despite nearly normal renal functions, occurring during treatment for giant cell arteritis, are described. The possible mechanisms for this association are discussed.

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http://dx.doi.org/10.1007/s10067-006-0366-3DOI Listing

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  • Guidelines for treating patients with calciphylaxis on renal replacement therapy are insufficient, resulting in challenges in their optimal treatment.
  • A 60-year-old male veteran on hemodialysis faced severe calciphylaxis-related pain and complications from chronic conditions, ultimately leading to his transfer to a specialized treatment center.
  • Despite available therapies, the interplay of complex pain, trauma history, and the patient's severe health issues contributed to a high rate of suffering and mortality, highlighting the need for improved care strategies in this group.
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