Introduction: In this article we begin by connecting the concept of simplicity of user interfaces of information systems with that of usability, and the concept of complexity of the problem-solving in information systems with the concept of usefulness. We continue by stating "the usability axiom" of medical information technology: information systems must be, at the same time, usable and useful. We then try to show why, given existing technology, the axiom is a paradox and we continue with analysing and reformulating it several times, from more fundamental information processing perspectives.
Discussion: We underline the importance of the concept of representation and demonstrate the need for context-dependent representations. By means of thought experiments and examples, we advocate the need for context-dependent information processing and argue for the relevance of algorithmic information theory and case-based reasoning in this context. Further, we introduce the notion of concept spaces and offer a pragmatic perspective on context-dependent representations. We conclude that the efficient management of concept spaces may help with the solution to the medical information technology paradox. Finally, we propose a view of informatics centred on the concepts of context-dependent information processing and management of concept spaces that aligns well with existing knowledge centric definitions of informatics in general and medical informatics in particular. In effect, our view extends M. Musen's proposal and proposes a definition of Medical Informatics as context-dependent medical information processing.
Summary: The axiom that medical information systems must be, at the same time, useful and usable, is a paradox and its investigation by means of examples and thought experiments leads to the recognition of the crucial importance of context-dependent information processing. On the premise that context-dependent information processing equates to knowledge processing, this view defines Medical Informatics as a context-dependent medical information processing which aligns well with existing knowledge centric definitions of our field.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ijmedinf.2006.05.039 | DOI Listing |
Gait Posture
December 2024
School of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada. Electronic address:
Background: To maintain standing balance, vestibular cues are processed and integrated with other sensorimotor signals to produce appropriate motor adjustments. Whole-body vestibular-driven postural responses are context-dependent and transformed based upon head and foot posture. Previous reports indicate the importance of intrinsic foot muscles during standing, but it is unclear how vestibular-driven responses of these muscles are modulated by alterations in stability and head posture.
View Article and Find Full Text PDFBiomacromolecules
January 2025
Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland.
Small molecules are frontline therapeutics for many diseases; however, they are often limited by their poor solubility. Therefore, hydrophobic small molecules are often encapsulated or prepared as pure drug nanoparticles. Navitoclax, used to eliminate senescent cells, is one such small molecule that faces challenges in translation due to its hydrophobicity and toxic side effects.
View Article and Find Full Text PDFSci Rep
January 2025
School of Mathematics and Computer, Wuhan Polytechnic University, Wuhan, 430048, China.
The rapid changes in the global environment have led to an unprecedented decline in biodiversity, with over 28% of species facing extinction. This includes snakes, which are key to ecological balance. Detecting snakes is challenging due to their camouflage and elusive nature, causing data loss and feature extraction difficulties in ecological monitoring.
View Article and Find Full Text PDFJ Neurosci
January 2025
Department of Physics, The Pennsylvania State University, University Park, PA 16802, USA
Generative models have diverse applications, including language processing and birdsong analysis. In this study, we demonstrate how a statistical test, designed to prevent overgeneralization in sequence generation, can be used to infer minimal models for the syllable sequences in Bengalese finch songs. We focus on the partially observable Markov model (POMM), which consists of states and the probabilistic transitions between them.
View Article and Find Full Text PDFFood Res Int
January 2025
School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China. Electronic address:
Intestinal microbiota could respond to dietary fibres that are fermented by the gut microbiota, like prebiotics. Nevertheless, the dynamics of intestinal microbial community longitudinally after prebiotics intake, are still largely unknown. The current study unrevealed the successional process of intestinal microbial community after inulin supplementation, and the effect of supplementation dosage thereof, based on analysis of 16S rRNA gene sequences in C57BL/6 mice.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!