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Persistent Thrombocytopenia of an Unexplained Cause in a Patient With Metastatic Renal Cell Carcinoma: A Case Report.

Cureus

December 2024

Surgical Oncology, Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Homi Bhabha Cancer Hospital, Tata Memorial Centre, Varanasi, IND.

Thrombocytopenia is a common complication in patients with solid tumors, particularly renal cell carcinoma (RCC), arising from mechanisms such as chemotherapy, direct tumor invasion, and paraneoplastic syndromes. Managing thrombocytopenia in advanced cancer presents significant challenges, often limiting therapeutic options and impacting patient outcomes. This case report describes a 62-year-old man with metastatic RCC complicated by persistent thrombocytopenia, unresponsive to both conventional treatments and novel therapies.

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Objectives: The purpose of our research was to understand intersections between health, spirituality and well-being in the Métis Nation of Alberta (MNA) Region 3.

Design: This Métis-guided, community-based, participatory research builds on our previous patient-oriented community-based study where we co-developed a qualitative structured survey with leaders, Elders and community members to explore health, spirituality and well-being in the MNA Region 3.

Setting: Métis people are affected by historical and contemporary impacts of colonisation.

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As the Army continues to adapt to evolving mission demands and global threats, those who execute the mission - both soldiers and Department of the Army (DA) civilians - must also adapt to changing occupational demands and requirements. Occupational stress within the military community is a threat to health and wellbeing that impacts not only individual soldiers and civilian personnel, but also units, families, and the broader military community. Hardiness is an operational requirement for military success, spirituality might be a means to positively impact soldier and DA Civilian hardiness.

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Objectives: The primary objective of this prospective review was to compare quality of life between patients undergoing endoscopic and open skull base approaches.

Study Type And Design: Prospective Review.

Methods: Five centers recruited consecutive patients treated surgically for skull base neoplasms between 2012 to 2018.

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Introduction: The birth and admission of a premature infant to the NICU is often an unexpected experience and a mental and spiritual challenge for families. Spiritual health is an influential factor affecting how a mother faces and endures a stressful situation. Improving the mother's spiritual health requires cognitive therapy approaches, including mindfulness techniques.

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