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We report the case of a 25-year-old man who was undergoing follow-up for neurofibromatosis type 1. The man underwent 68 Ga-DOTATOC PET/CT for a suspected well-differentiated duodenal neuroendocrine tumor. This examination did not reveal any significant uptake, whereas complementary 18 F-FDG PET/CT showed moderate 18 F-FDG uptake in the primary tumor as well as the adenopathy.
View Article and Find Full Text PDFA 52-year-old woman underwent esophagogastroduodenoscopy after an abnormal medical examination, which revealed a mass lesion over half the circumference of the superior duodenal angulus. Immunostaining was diffusely positive for somatostatin, synaptophysin, and chromogranin A. A 3 cm-sized mass in the pancreaticoduodenal region and multiple nodular lesions of a few mm in both lobes of the liver were revealed by CT.
View Article and Find Full Text PDFEuropean Neuroendocrine Tumor Society 2023 guidance paper for functioning pancreatic neuroendocrine tumour syndromes.
J Neuroendocrinol
August 2023
Department of Visceral, Thoracic and Vascular Surgery, Phillips-University Marburg and University Hospital Gießen Marburg GmbH, Marburg, Germany.
Article Synopsis
- * A functioning syndrome is characterized by a clinical presentation and high levels of specific hormones due to the presence of NETs, with several types identified, including insulinoma and gastrinoma.
- * The recommendations include approaches for biochemical, genetic, and imaging assessments, as well as management strategies for different hormonal syndromes in pancreatic NETs, particularly for well-differentiated tumors.
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