Objectives: To verify the effect of vibroacoustic stimulation on biophysical profile score, with a prospective randomised study.
Study Design: All women with singleton pregnancy, gestational age >or=30 weeks, intact membranes and biophysical profile score
Results: 1349 patients were randomised in group A and 1484 in group B (2833 in total). When comparing group A to B, application of vibroacoustic stimulation significantly decreased the number of positive tests (4.74% vs. 6.67%, p<0.05) and increased the prevalence of outcome criteria in this subgroup (positive likelihood ratio: 24.1 95% CI: 11.12-52.46 vs. 7.52 95% CI: 4.93-11.46), without altering perinatal outcome. Furthermore, specificity, positive predictive value and test accuracy were significantly improved, as well as negative predictive value for intrauterine death.
Conclusion: Vibroacoustic stimulation improves the efficiency of biophysical profile score by decreasing false positive tests and improving test accuracy and should be considered as a means of a more thorough fetal evaluation when fetal compromise is suspected.
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| http://dx.doi.org/10.1016/j.earlhumdev.2006.05.014 | DOI Listing |
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