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Modeling ocular surface ion and water transport by generation of lipid- and mucin-producing human Meibomian gland and conjunctival epithelial cells.
Am J Physiol Cell Physiol
January 2025
Laboratoire de Physiopathologie et Régulation des Transports Ioniques, Université de Poitiers, France.
Despite the importance of ocular surface in human physiology and diseases, little is known about ion channel expression, properties and regulation in ocular epithelial cells. Furthermore, human primary epithelial cells have rarely been studied in favor of rat, mouse and especially rabbit animal models. Here, we developed primary human Meibomian gland (hMGEC) and conjunctival (hConEC) epithelial cells.
View Article and Find Full Text PDFPrescriptions (Rx) for Prevention: Clinical Tools for Integrating Environmental Health into Pediatric Clinical Care.
J Public Health Manag Pract
January 2025
Department of Environmental Medicine and Public Health (Mr Bland, Dr Zajac, Ms Guel, Dr Pendley, Dr Galvez, Dr Sheffield), Icahn School of Medicine at Mount Sinai, New York, New York; Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (Mr Wilson), Boston, Massachusetts; Environmental Research and Translation for Health (EaRTH) Center (Ms Charlesworth), University of California, San Francisco, California; Community Engagement Core, Environmental Health Sciences Center at Department of Environmental Medicine (Dr Korfmacher), University of Rochester Medical Center, Rochester, New York; Pediatric Environmental Health and Cincinnati Children's Hospital Medical Center (Dr Newman), Cincinnati, Ohio; Philadelphia Regional Center for Children's Environmental Health, Center of Excellence in Environmental Toxicology, Perelman School of Medicine (Dr Howarth), University of Pennsylvania, Philadelphia, Pennsylvania; and Division of Academic General Pediatrics, Children's Hospital at Montefiore (Dr Balk), Albert Einstein College of Medicine, Bronx, New York.
The integration of environmental health (EH) into routine clinical care for children is in its early stages. The vision of pediatric EH is that all clinicians caring for children are aware of and able to help connect families to needed resources to reduce harmful environmental exposures and increase health-enhancing ones. Environmental exposures include air pollution, substandard housing, lead, mercury, pesticides, consumer products chemicals, drinking water contaminants, industrial facility emissions and, increasingly, climate change-related extreme weather and heat events.
View Article and Find Full Text PDFComparative study of inactivation efficacy of far-UVC (222 nm) and germicidal UVC (254 nm) radiation against virus-laden aerosols of artificial human saliva.
Photochem Photobiol
January 2025
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra, India.
Virus-laden aerosols play a substantial role in the spread of numerous infectious diseases, particularly in enclosed indoor settings. Ultraviolet-C (UVC) disinfection is known to be a highly efficient method for disinfecting pathogenic airborne viruses. Recent recommendations suggest using far-UVC radiation (222 nm) emitted by KrCl* (krypton-chloride) excimer lamps to disinfect high-risk public spaces due to lower exposure risks than low-pressure (LP) mercury lamps (254 nm).
View Article and Find Full Text PDFWet deposition of atmospheric Hg in a typical inland city in North China: Sources, influencing factors, and health risk assessment.
Environ Pollut
January 2025
College of Meteorology and Oceanography, National University of Defense Technology, Changsha, 410073, China.
Understanding the composition of mercury (Hg) in the atmosphere is important for confirming its sources and to preventing and reduce the production. To explore the morphological distribution characteristics of wet Hg concentrations in Xi'an Shaanxi Province, China, total Hg (THg), dissolved Hg (DTHg), reactive Hg (RTHg) and particulate-bound Hg (PTHg) (Hg insoluble in water) were measured at 72 precipitation in Xi'an from September 2020 to July 2022, and their average concentrations were 3.035 ± 3.
View Article and Find Full Text PDFIndication of air pollution based on the comparison of mercury and other elements in the faeces of marmots from the Western Carpathians and the Dzungarian Alatau.
Environ Sci Pollut Res Int
January 2025
Institute of High Mountain Biology Žilina University, Tatranská Javorina 7, 05956, Tatranská Javorina, Slovak Republic.
The Dzungarian Alatau in Central Asia and the Western Carpathians in Central Europe are exposed to anthropogenic sources of pollution that are impacting high-altitude mountain systems through long-range transport of emissions. Based on analyses of the autumn faeces of two species of marmots (Marmota baibacina from the alpine habitats of Zhongar Alatau National Park, Marmota marmota latirostris from the alpine habitats of the Western Tatras), we determined the environmental load of mercury and other chemical elements. Our results show significantly higher levels of total mercury amounts (p < 0.
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