Two proposed mechanisms for 4-thiouridine generation share key cysteine persulfide and disulfide intermediates, and indirect evidence of their existence has been previously reported; chemical trapping and mass spectrometry have now provided direct and definitive evidence of these key intermediates.

Download full-text PDF

Source
http://dx.doi.org/10.1039/b604040cDOI Listing

Publication Analysis

Top Keywords

persulfide disulfide
8
disulfide intermediates
8
direct evidence
4
evidence enzyme
4
enzyme persulfide
4
intermediates 4-thiouridine
4
4-thiouridine biosynthesis
4
biosynthesis proposed
4
proposed mechanisms
4
mechanisms 4-thiouridine
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!