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Primary myoepithelial carcinoma of the tibia: a close clinicoradiological mimicker of osteosarcoma.
BMJ Case Rep
January 2025
Pathology and Lab Medicine, AIIMS Jodhpur, Jodhpur, Rajasthan, India.
Myoepithelial tumours are rare and distinct entities with uncertain histogenesis. They occur primarily in major salivary glands and soft tissue around the head and neck. Bony involvement predominantly occurs in facial bones.
View Article and Find Full Text PDFClear cell myoepithelioma of palate: A rare case report with brief review of literature.
J Oral Maxillofac Pathol
October 2024
Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y.Patil Vidyapeeth, Pune, Maharashtra, India.
Myoepitheliomas are very rare salivary gland neoplasms seen mainly in the major salivary glands (~40%) followed by minor salivary glands (~21%). Palatal myoepitheliomas are rare, with clear cell types being even rarer. Due to the rarity of this tumor, it lacks specific features that are diagnostic in cytology.
View Article and Find Full Text PDFReappraisal of soft tissue myoepithelial tumors by DNA methylation profiling reveals an epigenetically distinct group of mostly fusion-driven neoplasms.
Virchows Arch
December 2024
Department of Pathology, MS 250, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Soft tissue myoepithelial tumors (METs) are diagnostically challenging tumors that require careful histologic and immunohistochemical characterization for accurate classification. Nearly half of METs show recurrent EWSR1 or FUS gene rearrangements with a diverse set of fusion partners. The diversity of fusion partners and lack of known driver abnormalities in many cases raises the question of whether METs represent a uniformly distinct tumor entity.
View Article and Find Full Text PDFADENOMYOEPITHELIOMA WITH CARCINOMA; EPITHELIAL-MYOEPITHELIAL CARCINOMA WITH EARLY PULMONARY METASTASIS.
J Ayub Med Coll Abbottabad
December 2024
Armed forces institute of Pathology, Rawalpindi-Pakistan.
Adenomyoepithelioma (AME) is a rare variant of breast neoplasm. It is a biphasic tumour characterized by small epithelial-lined spaces with inner luminal cells and outer of abluminal (myoepithelial) cells. Either - or both - of these two cells may rarely undergo malignant transformation.
View Article and Find Full Text PDFPrimary intracranial myoepithelioma in a child.
Childs Nerv Syst
November 2024
Department of Neurosurgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Myoepitheliomal tumours, associated with the salivary glands and certain soft tissue sites, are unusually encountered in the central nervous system (CNS). In the brain, although the most common location is the Sella, other areas can infrequently be involved. Such intracranial lesions are exceptionally rare in children.
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