[Primary mediastinal germ cell tumors].

Rev Assoc Med Bras (1992)

Departamento de Cirurgia Torácica, Centro de Tratamento e Pesquisa, Hospital do Câncer A.C. Camargo, Rua Prof. Antonio Prudente 211, Liberdade, Cep. 01509-900 São Paulo/SP.

Published: November 2006

Primary mediastinal germ cell tumors account for approximately 10% to 20% of all neoplasms of the mediastinum. It is generally accepted that they represent the malignant transformation of germinal elements without a gonadal focus. These tumors can be classified as teratomas, seminomas, nonseminomatous (yolk sac tumor, embryonal carcinoma, choriocarcinoma) and combined germ-cell tumors without teratomatous components. This review purposes to discuss the different primary mediastinal germ-cell tumors, their clinical presentation and options for treatment.

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http://dx.doi.org/10.1590/s0104-42302006000300020DOI Listing

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