Objective: To investigate the effect of exposure to damp housing on respiratory symptoms in women and men.
Method: We examined sex differences in the relationship between damp housing and respiratory symptoms in a cross-sectional survey of 1988 adults, 18 to 74 years of age, using a self-administered questionnaire. We used chi (2) and t-tests to test associations between potential risk factors and respiratory symptoms in men and women. We used multiple logistic regression modelling to determine adjusted odds ratios for several possible symptoms and home dampness. All multivariate analyses were stratified by sex.
Results: Men had a significantly higher prevalence of chronic wheeze compared with women. The prevalence of chronic wheeze, wheeze with shortness of breath, and allergy were higher for women reporting damp housing compared with those not reporting damp housing. No significant associations between damp housing and respiratory symptoms were found in men.
Conclusion: These data raise the possibility that women may be more susceptible to the effects of damp housing than men are.
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Front Immunol
December 2024
SinoMab BioScience Limited, Hong Kong, Hong Kong SAR, China.
Background: Alarmins mediate type 2 T helper cell (Th2) inflammation and serve as upstream signaling elements in allergic inflammation and autoimmune responses. The alarmin interleukin (IL)-25 binds to a multi-domain receptor consisting of IL-17RA and IL-17RB subunits, resulting in the release of Th2 cytokines IL-4, IL-5, IL-9 and IL-13 to drive an inflammatory response. Therefore, the blockage of IL-17RB via SM17, a novel humanized monoclonal antibody, offers an attractive therapeutic target for Th2-mediated diseases, such as asthma.
View Article and Find Full Text PDFJ Aging Soc Policy
November 2024
Care Policy and Evaluation Centre, London School of Economics and Political Science, London, UK.
Housing conditions and quality are well-established structural or social determinants of health. Poor quality housing also has the potential to affect care needs, but there is much less research on the topic, particularly on nonspecialist housing. Based on analysis of in-depth interviews with 44 people aged 65 and older living in England, their unpaid carers ( = 22), or as a carer-care recipient dyad ( = 6), (total = 72), this study sought to explore the perceived relationship between people's housing conditions and characteristics and their care needs.
View Article and Find Full Text PDFMicrobiome
November 2024
Department of Civil, Environmental & Geodetic Engineering, College of Engineering, The Ohio State University, 470 Hitchcock Hall, 2070 Neil Ave, Columbus, OH, 43210, USA.
Background: Increased risk of asthma and other respiratory diseases is associated with exposures to microbial communities growing in damp and moldy indoor environments. The exact causal mechanisms remain unknown, and occupant health effects have not been consistently associated with any species-based mold measurement methods. We need new quantitative methods to identify homes with potentially harmful fungal growth that are not dependent upon species.
View Article and Find Full Text PDFBMC Public Health
October 2024
Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Background: The indoor home environment plays a crucial role in determining the outcome of respiratory diseases, including asthma. Researchers, clinicians, and patients would benefit from self-reported questionnaires to assess indoor home environmental exposures that may impact on respiratory health.
Objective: To review self-reported instruments for assessing indoor home environmental exposures in asthma patients and to characterise their content, development, and psychometric properties.
Aust N Z J Public Health
October 2024
He Kāinga Oranga Housing and Health Research Programme, Department of Public Health, University of Otago, Wellington, New Zealand.
Objective: This study explores experiences of the Healthy Housing Initiative (HHI). Aimed at children at risk of housing-related illness, the HHI package includes the provision of items such as curtains, heaters, bedding, and insulation, advocacy to encourage landlords to install improvements, and education and advice to help people optimise their home environment.
Methods: We conducted semi-structured, in-depth interviews with 20 people living in rental housing who received the HHI intervention.
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