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[Impact of the development of anesthesia protocols on the incidence of peri-anesthetic anaphylactoid reactions].
Allerg Immunol (Paris)
October 2002
Service du Pr J.-P. Cassuto-Hôpital de l'Archet 1, 151, route St Antoine de Ginestière, BP 3079, 06202 Nice.
Introduction: What impact does the use of new drugs and latex gloves it have on the frequency and the severity of peri-anaesthetic anaphylactoid reactions? Does the evolution of in vitro techniques does represent a progress in the imputability of the substances at the origin of the shock?
The Methods: They include the letter from the anaesthetic doctor, the questioning by the allergologist, skin tests (Pricks, IDR) with the anaesthetic substances and the latex according to the GERAP protocol and the biologic tests (Human Basophilic Degranulation test (TDBH), Radio ImmunoAssay (RIA), leukotrienes E4 assay (LTC4), Flow Cytometry (CMF)).
The Results: 386 patients were explored (289 women and 88 men, mean age 41.5 years).
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