We assessed the fertility of 91 patients affected by unilateral cryptorchidism who were subjected to postpubertal orchidopexy in the last 15 years. All cases were clinically examined, evaluated by semen analysis and Doppler ultrasound of the spermatic artery. Twenty-two patients underwent testicular biopsy. The results indicate that orchidopexy is not the best treatment for postpubertal cryptorchid patients. After orchidopexy, 83.5% of patients were azoospermic or oligospermic, with or without asthenospermia.
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http://dx.doi.org/10.1159/000471680 | DOI Listing |
F1000Res
November 2024
Department of Urology, Rumah Sakit Dr Cipto Mangunkusumo, University of Indonesia, Central Jakarta, Jakarta, 10430, Indonesia.
Background: Undescended testes (UDT) is a condition where one or both testes is absent in the scrotum. The general age recommendation in which the treatment should be performed is before 18 months old due to the infertility risk and malignancy in later life. In post-pubertal UDT, the current guideline recommends orchiectomy; however, the strength rating of this recommendation is weak.
View Article and Find Full Text PDFTheriogenology
August 2024
Department of Animal Science and Biotechnology, Kyungpook National University, Sangju, 37224, Republic of Korea; Research Institute for Innovative Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea; Department of Horse, Companion and Wild Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea. Electronic address:
Spermatogonial stem cells (SSCs) are essential for the maintenance of male fertility and survival of species. Environmental conditions, notably heat stress, have been identified as important causes of male infertility and have a negative impact on SSCs. Animals with cryptorchid testes (CT) are optimal models for the study of long-term heat stress-related changes in germ cells.
View Article and Find Full Text PDFReprod Domest Anim
April 2024
Department of Animal Science and Biotechnology, Kyungpook National University, Sangju, Republic of Korea.
Cryptorchidism affects spermatogenesis and testis development, often resulting in stallion subfertility/infertility. This study aims to identify the specific germ cells impacted by cryptorchism in stallions. In a previous study, we found that PGP9.
View Article and Find Full Text PDFAndrology
November 2024
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Centre for Population Health Research, University of Turku, Turku, Finland.
Background: Testicular volume is a marker of male pubertal development. Various clinical conditions and their treatments may influence testicular growth.
Objectives: To create ruler-based age-dependent pubertal testicular volume references that enable calculation of standard deviation (SD) scores.
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