Our study revealed morphological changes in the two organs of Guinea pig kidney and suprarenal gland exposed to hyperbaric-hyperoxic environment. Proceeding from these data and knowing that in hyperbaric-hyperoxic environment the production of free oxygen radicals is increased, while the afferent arterioles undergo vasoconstriction, with direct implications on the cellular metabolism, our study puts forth the survey of the influence of hyperoxic environment on kidneys and adrenal gland - complex organs which are exposed to stress.
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Diving Hyperb Med
December 2023
Department of Anesthesiology, Amsterdam University Medical Center, location AMC, 1100 DD, Amsterdam, The Netherlands.
Pulmonary oxygen toxicity (POT), an adverse reaction to an elevated partial pressure of oxygen in the lungs, can develop as a result of prolonged hyperbaric hyperoxic conditions. Initially starting with tracheal discomfort, it results in pulmonary symptoms and ultimately lung fibrosis. Previous studies identified several volatile organic compounds (VOCs) in exhaled breath indicative of POT after various wet and dry hyperbaric hypoxic exposures, predominantly in laboratory settings.
View Article and Find Full Text PDFUndersea Hyperb Med
October 2019
Environmental Physiology & Medicine Lab, Department of Biomedical Sciences, University of Padova, Italy.
Introduction: Hyperbaric oxygen (HBO₂) therapy and use of enriched air can result in oxidative injury affecting the brain, lungs and eyes. HBO₂ exposure during diving can lead to a decrease in respiratory parameters. However, the possible effects of acute exposure to oxygen-enriched diving on subsequent spirometric performance and oxidative state in humans have not been recently described recently.
View Article and Find Full Text PDFPLoS One
June 2017
Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Saturation diving (SD) is one of the safest techniques for tolerating hyperbaric conditions for long durations. However, the changes in the human plasma protein profile that occur during SD are unknown. To identify differential protein expression during or after SD, 65 blood samples from 15 healthy Japanese men trained in SD were analyzed by two-dimensional fluorescence difference gel electrophoresis.
View Article and Find Full Text PDFIntroduction: Exposure to the confined hyperbaric, hyperoxic environment of the saturation chamber poses a number of unique physiological challenges to divers. Appropriately tailored training, nutrition and health programs may help support the body to cope with and overcome these challenges.
Aim: To describe the self-reported habits and attitudes of saturation divers toward issues related to health, lifestyle, nutrition and physical activity.
Extrem Physiol Med
January 2016
School of Health Sciences, Robert Gordon University, Aberdeen, AB10 7QG UK ; Laboratory of Applied Nutrition and Metabolism, School of Physical Education and Sport, University of Sao Paulo, São Paulo, Brazil.
Saturation diving is an occupation that involves prolonged exposure to a confined, hyperoxic, hyperbaric environment. The unique and extreme environment is thought to result in disruption to physiological and metabolic homeostasis, which may impact human health and performance. Appropriate nutritional intake has the potential to alleviate and/or support many of these physiological and metabolic concerns, whilst enhancing health and performance in saturation divers.
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