We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291063 | PMC |
| http://dx.doi.org/10.3201/eid1207.060107 | DOI Listing |
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