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Effect of different doses of oral olanzapine to prevent postoperative nausea and vomiting after laparoscopic surgery in high-risk patients: A randomised controlled trial.
J Perioper Pract
January 2025
Department of Anaethesia, Intensive Care and Pain Management Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Background: We conducted this study to compare the efficacy of oral 10 and 5 mg olanzapine for the prevention of postoperative nausea and vomiting.
Methods: Notably, 135 female patients between the ages of 18 and 50 years, classed as American Society of Anaesthesiologists I and II, who underwent elective laparoscopic gynaecological surgery under general anaesthesia were randomly assigned to one of three groups (45 each) to receive perioperative 5 or 10 mg oral olanzapine (OL5 and OL10 groups), or a placebo (in the control group). Postoperation, we recorded the occurrence and severity of postoperative nausea and vomiting within 24 h, the number of patients who received antiemetics and any associated side effects.
Use of images to assess awareness and use of emerging nicotine pouch products.
Nicotine Tob Res
January 2025
Institute for Nicotine and Tobacco Studies, Rutgers Health, New Brunswick, NJ, USA.
Introduction: Accurate measurement is critical for understanding the population health impact of nicotine pouches, yet precise, standardized measures of nicotine pouch use are lacking, possibly driving disparate prevalence estimates across studies. We implemented a split sample survey experiment to assess the impact of including a product image when asking about nicotine pouches.
Methods: We randomized an online sample of US adults ages 18-45 (N=2,130) recruited through the February 2023 wave of the Rutgers Omnibus Study to view either a text-only or text-plus-image description of oral nicotine pouches before being asked about awareness of the products.
The contribution of cognitive disengagement syndrome symptoms to depressive symptoms among pediatric brain tumor survivors.
J Pediatr Psychol
January 2025
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.
Objective: Pediatric brain tumor survivors (PBTS) are at risk for neurocognitive late effects that can resemble symptoms of cognitive disengagement syndrome (CDS). In the current study, we compared the CDS symptoms of PBTS to those of healthy comparison classmates (CC) and examined whether CDS might explain group differences in depressive symptoms. We also explored whether CDS symptoms were associated with engagement-based coping strategies and stress responses, thereby testing one mechanism by which CDS could lead to affective difficulties.
View Article and Find Full Text PDFPediatric COVID-19 severity by SARS-CoV-2 lineage and vaccine status in Canada: an IMPACT study.
Pediatr Res
January 2025
Centre for Global Child Health, The Hospital for Sick Children, Toronto, ON, Canada.
Background: Interpretations of pediatric COVID-19 severity are complicated by novel lineages and COVID-19 vaccine introduction. We estimated the risk of severe COVID-19 by SARS-CoV-2 lineage and vaccination status among hospitalized Canadian children.
Methods: Data were collected through the Canadian Paediatric Surveillance Program (April 2020-May 2021) and Canadian Immunization Monitoring Program, ACTive (June 2021-December 2022).
Comparison of continuous non-invasive blood pressure measurement using Vitalstream™ to invasive Intraarterial pressure in pediatric surgery.
J Clin Anesth
January 2025
Caretaker Medical, 941 Glenwood Station Ln #301, Charlottesville, VA 22901, United States of America.
Background: Accurate blood pressure monitoring is essential in many clinical scenarios for adults and children and, when continuous measurement is critical, necessitates the insertion of an arterial line. A novel continuous non-invasive arterial pressure monitoring device using a pulse contour algorithm (Pulse Decomposition Analysis), Vitalstream™, is approved by the United States Food and Drug Administration for use in adults. In this study the performance and accuracy of the device compared to intraarterial blood pressure monitoring were assessed in children ages 2-17 undergoing major surgeries.
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