Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4065/81.7.869 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
National recommendations of the Croatian Chamber of Medical Biochemists and Working group for Laboratory hematology of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Management of samples with suspected EDTA-induced pseudothrombocytopenia.
Biochem Med (Zagreb)
October 2024
Department of Medical Laboratory Diagnostics, University Hospital Sveti Duh, Zagreb, Croatia.
Article Synopsis
- Pseudothrombocytopenia (PTCP) is a rare issue where platelet counts appear low due to aggregation, leading to possible misdiagnoses and unsafe clinical decisions if not recognized quickly.
- The most frequent cause of PTCP is ethylenediaminetetraacetic acid (EDTA), and there are various management strategies documented, though expert guidance is limited.
- A collaborative group in Croatia developed minimal recommendations to help standardize the detection and reporting of platelet counts from EDTA-induced PTCP, aimed at laboratory professionals and healthcare providers involved in blood sample management.
Thrombocytopenia is a rare but serious complication of the intravenous glycoprotein IIb/IIIa (GPIIb/IIIa; integrin αIIbβ3) receptor inhibitors (GPIs), abciximab, eptifibatide, and tirofiban. The thrombocytopenia ranges from mild (50 000-100 000 platelets/μL), to severe (20 000 to <50 000/μL), to profound (<20 000/μL). Profound thrombocytopenia appears to occur in <1% of patients receiving their first course of therapy.
View Article and Find Full Text PDFKey Clinical Message: EDTA-dependent pseudothrombocytopenia as well as myelosuppression should be suspected when thrombocytopenia occurs in patients with autoimmune disease during chemotherapy.
Abstract: A patient with pancreatic cancer and ulcerative colitis developed transient ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia with exacerbation of ulcerative colitis during chemotherapy. Unfortunately, pseudothrombocytopenia could not be immediately detected because thrombocytopenia was masked by a reasonable time course of adverse events associated with chemotherapy and ulcerative colitis recurrence.
Severe Thrombocytopenia with Acute Cerebral Infarction: A Case Report and Literature Review.
Niger J Clin Pract
July 2023
Department of VIP Unit, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
Common causes of thrombocytopenia include pseudo-thrombocytopenia, splenomegaly, decreased bone marrow production, and increased platelet destruction or depletion. The main clinical manifestation is bleeding, and thrombosis-related complications are rare. This article reports an 87-year-old woman with severe thrombocytopenia for more than 7 years.
View Article and Find Full Text PDFEthylene Diamine Tetra Acetate-Induced Pseudo Thrombocytopenia (EDTA-PTCP) in an Adolescent: A Case Report.
Cureus
May 2023
Pathology, Satya Scans and Laboratories, Rajahmundry, IND.
Ethylene diamine tetra acetate-induced pseudo thrombocytopenia (EDTA-PTCP) is a fictitious laboratory condition that is associated with platelet clumping, leading to falsely low platelet counts. This fictitious occurrence can lead to expensive, time-consuming, and invasive diagnostic procedures. It may also result in the application of unnecessary therapies,although it is not linked to any hemorrhagic symptoms or platelet malfunction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!