Background: Tight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control.
Aim: To assess the effect and costs of rapid testing for glycated haemoglobin (HbA1c) in people with type 2 diabetes.
Design Of Study: Pragmatic open randomised controlled trial.
Setting: Eight practices in Leicestershire, UK.
Method: Patients were randomised to receive instant results for HbA1c or to routine care. The principal outcome measure was the proportion of patients with an HbA1c <7% at 12 months. We also assessed costs for the two groups.
Results: Of the 681 patients recruited to the study 638 (94%) were included in the analysis. The mean age at baseline was 65.7 years (SD = 10.8 years) with a median (interquartile range) duration of diabetes of 4(1-8) years. The proportion of patients with HbA1c < 7% did not differ significantly between the intervention and control groups (37 versus 38%, odds ratio 0.95 [95% confidence interval = 0.69 to 1.31]) at 12 months follow up. The total cost for diabetes-related care was 390 UK pounds per patient for the control group and 370 UK pounds for the intervention group. This difference was not statistically significant.
Conclusion: Near-patient testing for HbA1c alone does not lead to outcome or cost benefits in managing people with type 2 diabetes in primary care. Further research is required into the use of rapid testing as part of an optimised patient management model including arrangements for patient review and testing.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872061 | PMC |
Trials
January 2025
Department of Neurology, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
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Eli Lilly and Company, Indianapolis, Indiana, USA.
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Diabetes Obes Metab
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Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK.
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