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http://dx.doi.org/10.1007/s00277-006-0163-8 | DOI Listing |
Agri
January 2025
Division of Algology, Department of Physical Medicine and Rehabilitation, Marmara University Faculty of Medicine, İstanbul, Türkiye.
The superior hypogastric plexus (SHP) contains afferent nociceptive fibers from the pelvic structures, thus the SHP block is employed in the chronic pelvic pain (CPP) treatment in patients who do not respond to conservative treatments. A 60-year-old female patient, who did not respond to conservative treatment, underwent SHP neurolytic block after a successful diagnostic block. An excessive oblique angle approach was applied due to physical restrictions, the needle passed through the intervertebral disc resulting in the contralateral side SHP block, and the procedure was also repeated to the other side SHP.
View Article and Find Full Text PDFBackground: The molecular of intervertebral disc degeneration (IVDD) is still unclear. When it comes to treating decoction, traditional Chinese medicine is effective. In particular, the Duhuo (Radix Angelicae Biseratae) may be particularly helpful.
View Article and Find Full Text PDFFront Surg
January 2025
Department of Traditional Chinese Medicine, Guilin People's Hospital, Guilin, Guangxi, China.
Introduction: To develop an intelligent system based on artificial intelligence (AI) deep learning algorithms using deep learning tools, aiming to assist in the diagnosis of lumbar degenerative diseases by identifying lumbar spine magnetic resonance images (MRI) and improve the clinical efficiency of physicians.
Methods: The PP-YOLOv2 algorithm, a deep learning technique, was used to design a deep learning program capable of automatically identifying the spinal diseases (lumbar disc herniation or lumbar spondylolisthesis) based on the lumbar spine MR images. A retrospective analysis was conducted on lumbar spine MR images of patients who visited our hospital from January 2017 to January 2022.
J Orthop Surg Res
January 2025
Department of Orthopedic Surgery, Beijing Chaoyang Hospital, Capital Medical University of China, Gongti South Rd, No. 8, Beijing, 100020, China.
Objective: This study aims to investigate changes in matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) levels in the intervertebral discs of New Zealand white rabbits under simulated overload and microgravity conditions, focusing on the expression of MMP1, MMP3, and TIMP1. The findings aim to provide a theoretical foundation for preventing and delaying lumbar disc degeneration in these environments.
Methods: Overload was simulated using an animal centrifuge, and microgravity was mimicked through tail suspension.
Medicine (Baltimore)
January 2025
Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, PR China.
Rationale: Alkaptonuria (AKU) is a rare, inherited metabolic disease caused by deficient activity of homogentisic acid oxidase, leading to the accumulation of homogentisic acid and its oxidized product, benzoquinone acetic acid. These compounds cause black discoloration of cartilage, degeneration, inflammation, and calcification of intervertebral disks and large joints, resulting in pain and impaired quality of life. Despite its debilitating effects, there are no curative treatments for AKU, and management remains supportive.
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