Extractive substances obtained from the bark of aspen (Populus tremula L.) with the use of petroleum ether (lipids I) and diethyl ether (lipids II) have exhibited high antibacterial activity with respect to Streptococcus pneumoniae and Haemophilus influenzae, causing 100% cell destruction. The minimum inhibiting concentration for S. pneumoniae has been found to be 0.5 - 50 mg/ml for lipids I and 0.0005 - 0.5 mg/ ml for lipids II, depending on the strain of bacteria. The antibacterial activity of rhytidome extracts is somewhat higher than that of phloem extracts. To suppress the growth of H. influenzae, more concentrated solutions of these extracts from 30 to 50 mg/ml are needed. Staphylococcus aureus was resistent in lipids. The action of temperature, mineral acids and alkali on lipids, as well as prolonged storage of strains in a refrigerator decreases the antibacterial activity of extracts under study.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Investigation of the antibacterial activity, cytotoxicity, and effects on enamel and composite resin of mouthwash formulations prepared with three different Boron compounds.
Clin Oral Investig
January 2025
Professor, Department of Biology, Faculty of Science, Dokuz Eylul University, Izmir, Tr-35340, Turkey.
Objective: This study investigated the use of oral rinse solutions formulated with boron-containing compounds, known for their antibacterial activity, as an alternative to chlorhexidine (CHX).
Material And Method: Boron nitride (BN), boric acid (BA) and sodium borate (SB) were used in the study. BN was used in nanosuspension (BN-NS) due to its low solubility in water.
Rational Design of Natural Xanthones Against Gram-negative Bacteria.
Adv Sci (Weinh)
January 2025
National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing, 100193, China.
Most antibiotics are ineffective against Gram-negative bacteria owing to the existence of the outer membrane (OM) barrier. The rational design of compounds to expand their antibacterial spectra of antibiotics solely targeting Gram-positive pathogens remains challenging. Here, the design of skeletons from natural products to penetrate the OM are deciphered.
View Article and Find Full Text PDFFacile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium-Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing.
Adv Healthc Mater
January 2025
College of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian, 350108, China.
Multifunctional hydrogels hold significant promise for promoting the healing of infected wounds but often fall short in inhibiting antibiotic-resistant pathogens, and their clinical translation is limited by complex preparation processes and high costs. In this study, a multifunctional hydrogel is developed by combining metal-phenolic networks (MPNs) formed by tannic acid (TA) and gallium ions (Ga⁺) with chitosan (CS) through a simple one-step method. The resulting CS-TA-Ga⁺ (CTG) hydrogel is cost-effective and exhibits desirable properties, including injectability, self-healing, pH responsiveness, hemostasis, antioxidant, anti-inflammatory, and antibacterial activities.
View Article and Find Full Text PDFLocation of 7-Aminoactinomycin D in Micellar Medium Depends on Ionic Nature of the Surfactant Head Group.
Luminescence
February 2025
Department of Chemistry, University of Calcutta, Kolkata, India.
7-Aminoactinomycin D (7AAMD) is the fluorescent analogue of the anticancer drug actinomycin D (AMD). In order to overcome toxic side effects and enhanced bioavailability of 7AAMD, micellar drug carrier systems could be useful. We have used cationic (hexadecetyltrimethylammonium bromide [CTAB]), anionic (sodium dodecyl sulphate [SDS]) and non-ionic (t-octylphenoxypolyoxyethanol, Triton-X100 [TX 100]) surfactants to prepare micelle.
View Article and Find Full Text PDFInvestigating the protective effect of Rosa damascena nanogel on collagenase and elastase activity and UVB-induced dermal damage: A rodent model approach to skin photoaging.
Photochem Photobiol
January 2025
Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
While aging inevitably changes our skin, this complex biological process involves much more than just getting older. As the body's largest organ, the skin constantly safeguards us from harmful environmental pathogens and plays a key role in overall well-being. This study investigated the development and evaluation of a nanogel containing Rosa damascena essential oil for its potential anti-aging properties.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!