AI Article Synopsis
- The study aimed to identify polymorphic Y chromosome markers in the Chinese Han population and gather related genetic data.
- Genotyping was performed on 23 Y chromosome markers in 160 unrelated Chinese males using specialized PCR and electrophoresis techniques, revealing genetic polymorphism in 20 markers.
- A total of 35 haplogroups were identified, indicating high genetic diversity, which can be useful for forensic applications and understanding population evolution.
Article Abstract
To search polymorphic Y chromosome biallelic markers in Chinese Han population, and obtain their population genetic data. Genotyping of 23 biallelic markers on human Y chromosome (M7, M9, M50, M88, M89, M95, M111, M117, M119, M121, M122, M134, M159, M164, M175, M214, LINE1, MSY2, RPS4Y711, SRY465, IMS-JST164520, IMS-JST021354 and IMS-JST003305) were carried out in a sample of 160 unrelated Chinese male individuals living in Wuhan using fragment length discrepant allele specific PCR (FLDAS-PCR) and PAGE technique. In all 23 biallelic markers, genetic polymorphism were identified for 20 loci in Wuhan Han population except for M50, M159 and M164, and the ranges of gene diversity (GD) were 0.0126-0.4855. A total of 35 different haplogroups (Hg1-35) were observed and the haplogroup diversity (HD) was 0.9471. The haplogroups formed by 20 biallelic markers are highly polymorphic, and can be used in forensic science and population evolution studies.
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