In vivo transduction of an Stx-encoding phage in ruminants.

Appl Environ Microbiol

Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50010, USA.

Published: July 2006

We assessed the ability of a kanamycin-marked Stx phage to move into a commensal, ovine Escherichia coli strain in the ruminant gastrointestinal tract. Transduction was detected in 19/24 sheep tested, resulting in the recovery of 47 transductants. Subtherapeutic doses of the quinolone antibiotic enrofloxacin did not increase the rate of transduction.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489371PMC
http://dx.doi.org/10.1128/AEM.00157-06DOI Listing

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