We aimed to report a case with rhabdomyolysis related to hyponatremia and/or its correction. A 32-year-old male schizophrenic patient on ziprasidone treatment was admitted to the hospital following a seizure. Patient had primary polydipsia and secondarily developed hyponatremia. After the correction of hyponatremia, due to the high liver enzyme levels, he was diagnosed as rhabdomyolysis. Although the role of antipsychotics in this situation is speculative, development of rhabdomyolysis related to hyponatremia and/or its correction should not be underestimated and should be assessed thoroughly.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pnpbp.2006.05.020 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sexual dysfunctions associated with antipsychotic drug intake: a retrospective analysis of the FDA adverse events reporting system (FAERS).
Naunyn Schmiedebergs Arch Pharmacol
January 2025
University Clinic for Psychiatry and Psychotherapy, Brandenburg Medical School Immanuel Klinik Rüdersdorf, Seebad 82/83, Rüdersdorf bei Berlin, 15562, Rüdersdorf, Germany.
Sexual dysfunctions (SD) are common and debilitating side effects of antipsychotics. The current study analyzes the occurrence of antipsychotic-related SD using data from the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS). FAERS was queried for sexual dysfunction adverse events (encoded by 35 different MedDRA preferred terms) secondary to amisulpride, aripiprazole, chlorprothixene, clozapine, haloperidol, loxapine, olanzapine, pipamperone, quetiapine, risperidone, and ziprasidone from 2000 to 2023.
View Article and Find Full Text PDFCardiac safety of antipsychotic medications in pediatric and adolescent population: a systematic review and pathways for future research.
Eur J Pediatr
November 2024
Child and Adolescent Psychiatry Unit, Neuroscience and Human Genetics Department, Meyer Children's Hospital IRCCS 50139, Florence, Italy.
Article Synopsis
- A systematic review analyzed 10 studies involving 523 patients to evaluate how various antipsychotic medications impact the QTc interval in youngsters.
- Results indicated that risperidone and aripiprazole had minimal QTc effects, while other drugs like quetiapine and pimozide showed varying levels of prolongation, highlighting a need for more research and careful monitoring when prescribing these medications.
Drug-associated glaucoma: A real-world study based on the Food and Drug Administration adverse event reporting system database.
Clin Exp Ophthalmol
October 2024
Xiamen University affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Background: This study aims to assess the risk of drug-associated glaucoma and track its epidemiological characteristics using real-world data.
Methods: Adverse event reports from the Food and Drug Administration Adverse Event Reporting System (FAERS) from January 2004 to December 2023 were analysed. Disproportionality analysis and the Bayesian Confidence Propagation Neural Network algorithm were used.
Effects of six antipsychotic drug treatment regimens on short-term heart rate variability in patients with schizophrenia.
Int J Psychiatry Med
October 2024
Department of Functional Examination, The Guangxi Zhuang Autonomous Region Brain Hospital, Liuzhou, China.
Objective: Many antipsychotic drugs have cardiac side effects due to their pharmacological actions. Heart rate variability (HRV) analysis can be used as a potential indicator of cardiotoxicity in cases where a decrease in HRV occurs after the administration of antipsychotics such as clozapine. The purpose of this study was to explore the effects of 6 antipsychotic drug regimens on short-term HRV in patients with schizophrenia.
View Article and Find Full Text PDFObjective: This study aims to compare the risks of different antipsychotics in causing hyperprolactinemia, taking into account the age, gender, and onset time.
Materials And Methods: We searched the FDA Adverse Event Reporting System (FAERS) from January 1, 2004, to March 31, 2022, for reports of hyperprolactinemia treated with antipsychotics. We evaluated the association between antipsychotics and the risk of hyperprolactinemia using reporting odds ratio (ROR) based on a disproportionality analysis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!