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Chapter 3: IMPACT OF PRIMARY HYPERPARATHYROIDISM.
Ann Endocrinol (Paris)
January 2025
Hospices Civils de Lyon, Groupement Hospitalier Est, Endocrinology Federation, Lyon, France.
At present, primary hyperparathyroidism is most often discovered in an asymptomatic patient, but can sometimes be revealed by a renal or bone complications. In all cases, a full work-up is recommended, with assessment of renal function (glomerular filtration rate), 24-hour calciuria, screening for risk factors for lithiasis, and renal and urinary tract imaging (ultrasound or CT scan) to look for stones or nephrocalcinosis. Bone densitometry, with measurements of the spine, femur and radius, is the recommended reference test for demineralization.
View Article and Find Full Text PDFFirst in-human gadolinium K-edge imaging with spectral photon counting CT.
Diagn Interv Imaging
January 2025
Department of Cardiovascular and Thoracic Radiology, Hôpital Louis Pradel, Hospices Civils de Lyon, Lyon 69002, France; CREATIS, CNRS UMR 5220, INSERM U1206, INSA-Lyon, University Claude Bernard Lyon 1, Villeurbanne 69100, France.
Measurement of biomechanical properties of transversely isotropic biological tissue using traveling wave expansion.
Med Image Anal
January 2025
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China; Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai 200040, China; National Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy (NERC-AMRT), Shanghai Jiao Tong University, Shanghai 200040, China; Department of Radiology, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address:
The anisotropic mechanical properties of fiber-embedded biological tissues are essential for understanding their development, aging, disease progression, and response to therapy. However, accurate and fast assessment of mechanical anisotropy in vivo using elastography remains challenging. To address the dilemma of achieving both accuracy and efficiency in this inverse problem involving complex wave equations, we propose a computational framework that utilizes the traveling wave expansion model.
View Article and Find Full Text PDFA Homozygous ATP2A2 Variant Alters Sarcoendoplasmic Reticulum Ca-ATPase 2 Function in Skeletal Muscle and Causes a Novel Vacuolar Myopathy.
Neuropathol Appl Neurobiol
February 2025
Department of Neurology, Neuromuscular Diseases Unit, Hospital de la Santa Creu i Sant Pau, Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.
Aims: Sarcoendoplasmic reticulum Ca-ATPase 2 (SERCA2), encoded by ATP2A2, is a key protein involved in intracellular Ca homeostasis. The SERCA2a isoform is predominantly expressed in cardiomyocytes and type I myofibres. Variants in this gene are related to Darier disease, an autosomal dominant dermatologic disorder, but have never been linked to myopathy.
View Article and Find Full Text PDFEquitable Stroke Care for a Growing Population: The Need for Cultural Sensitivity.
Circ Cardiovasc Qual Outcomes
January 2025
Department of Medicine, Cardiovascular Division, University of Virginia Health, Charlottesville, Virginia, USA. (P.F.R.L., C.C.S.).
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