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Efficacy of bolus injections of landiolol hydrochloride as premedication in coronary artery CT angiography.
Insights Imaging
January 2025
Institute of Radiology, LKH Graz II, Graz, Austria.
Purpose: To assess the efficacy of bolus injections of landiolol hydrochloride as premedication in coronary artery CT angiography (CCTA).
Methods: The study population consisted of 37 patients (17 female; median age, 56 years; IQR, 19 years; range, 19-88 years) who underwent CCTA after intravenous injection of landiolol hydrochloride due to a heart rate > 60 bpm. Landiolol hydrochloride was administered in a stepwise manner until a heart rate of ≤ 60 bpm was achieved or a maximum dose of 60 mg was reached after six injections.
Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery.
Expert Opin Drug Deliv
January 2025
Smart Materials, Istituto Italiano di Tecnologia, Genova, Italy.
Introduction: Chronic non-healing wounds have emerged as a significant global healthcare challenge. Biofilm induced wound infections has been widely acknowledged. Despite the advanced understanding of biofilm formation, the existing approaches for diagnosing biofilms in wounds remain considerably suboptimal.
View Article and Find Full Text PDFNon-Genetic Biomarkers in Merkel Cell Carcinoma: Prognostic Implications and Predictive Utility for Response to Anti-PD-(L)1 Immune Checkpoint Inhibitors.
Exp Dermatol
January 2025
Department of Medicine and Division of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Merkel cell carcinoma (MCC) is a skin cancer that arises due to either Merkel cell polyomavirus infection (MCPyV) or ultraviolet (UV) radiation exposure, presenting primarily in the head and neck region of fair-skinned males. The recent success of PD-(L)1 immune checkpoint inhibitors (ICIs) in locally advanced/metastatic MCC, with an objective response rate (ORR) around 50% and improved survival, as a first-line treatment has moved ICIs to the forefront of therapy for MCC and generated interest in identifying biomarkers to predict clinical response. The MCC tumour microenvironment (TME) contains various components of the adaptive and innate immune system.
View Article and Find Full Text PDFExploring Inclusion by Creating Inclusion: A World Café Among Nurse Scientists.
West J Nurs Res
January 2025
Golden Apple Healing Arts, LLC, Wauwatosa, WI, USA.
Background: The concept of inclusion within diversity, equity, and inclusion has broad meanings and implications and has not been explored in nursing through a World Café.
Purpose: To describe the process and experiences of 9 nurse scientists who hosted a World Café focused on inclusion, to share participants' insights, and to offer considerations to advance inclusion in nursing.
Approach: We hosted and encouraged active participation in a World Café that focused on 7 inclusion topics in nursing during the 2024 Midwestern Nursing Research Society Annual Research Conference.
State of Lung Cancer in Egypt: Moving Towards Improved Guidelines for Prevention, Screening, Treatment, and Clinical Care Programs.
JTO Clin Res Rep
January 2025
Icahn School of Medicine at Mount Sinai, New York, New York.
Lung cancer remains a leading cause of cancer-related mortality globally and presents significant challenges in Egypt. In 2023, the first annual meeting of the Thoracic Oncology Multidisciplinary Faculty, organized by the Egyptian Cancer Research Network and the Egyptian Society of Respiratory Neoplasms, was held in Cairo, Egypt. The meeting aimed to address gaps in lung cancer management across Egypt and the broader Middle East and North Africa region.
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