We analyzed 3,475 human immunodeficiency virus sequences and 241 therapeutic histories. The L74I mutation was carried by 7% of viruses. L74I was strongly associated with T215F, K70R, and V75M/S/T/A mutations and increased with the number of thymidine analog mutations. It seemed to be linked to the use of abacavir or efavirenz.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489786 | PMC |
| http://dx.doi.org/10.1128/AAC.00092-06 | DOI Listing |
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