AI Article Synopsis
- Alcohol abuse can lead to various movement disorders like tics and tremors, but it has a unique relationship with essential tremor (ET) and myoclonus-dystonia (M-D).
- The article explores how alcohol may provide temporary relief for symptoms in both ET and M-D, and discusses the phenomenon of self-medication among individuals with these disorders.
- Researchers are investigating the underlying mechanisms of how alcohol affects these conditions, which could pave the way for new treatment methods.
Article Abstract
Many movement disorders, including tics, chorea, tremor, myoclonus and parkinsonism, may result from substance abuse. However, alcohol in particular is associated in a more complex manner with two specific movement disorders, essential tremor (ET) and myoclonus-dystonia (M-D). In this review we discuss the comorbidity of alcohol abuse in both ET and M-D, the ameliorative effects of alcohol in both diseases, and review the data evaluating alcohol abuse secondary to self-medication. We also discuss shared pathophysiologic mechanisms in the understanding of both of these disorders, as the elucidation of the mechanisms by which alcohol exerts its effects may lead to novel therapeutic approaches.
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| http://dx.doi.org/10.1111/j.1369-1600.2006.00017.x | DOI Listing |
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