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Deciphering signaling control by phosphoproteome using mass spectrometry. | LitMetric

Deciphering signaling control by phosphoproteome using mass spectrometry.

Protein Pept Lett

Department of Surgery, Division of Urology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

Published: July 2006

Analysis of changes in genes and protein profiles provides invaluable information to understand the activities and functions of proteins. However, their activities are further regulated by post-translational modifications, such as glycosylation and phosphorylation. Cell growth and apoptotic pathways are good examples of demonstrating the roles of phosphorylation in activation of protein cascades upon stimulation.

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Source
http://dx.doi.org/10.2174/092986606776819664DOI Listing

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