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Left ventricular diastolic dysfunction in obese women. | LitMetric

Aim: To determine the direct effect of obesity on echocardiographic indices of diastolic left ventricular function

Methods: 44 obese (BMI > or =25 kg/m2) and 45 normal weight women were studied. They had no other pathological conditions. Echocardiographic indices of diastolic function were obtained, and dysfunction was assumed when at least two values differed by > or =2 SD from the normal weight group.

Results: In obese subjects, the values of maximum velocity of active mitral filling (A) were increased and pulmonary diastolic velocity was decreased significantly (p< 0,01); all other diastolic variables were unchanged. Subclinical diastolic dysfunction tend to be more prevalent among obese subjects but it was not significantly different from non obese (p= 0.11), being present in nine obese (20.5%) and 4 normal (8.9%) subjects.

Conclusion: Subclinical left ventricular diastolic dysfunction is present in obese women.

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