Purpose: To study the audiovestibular function in patients of long-term alcohol dependence and compare these changes with social users of alcohol and complete abstainers.
Material And Methods: This was a prospective study of 20 randomly selected patients of long-term alcohol dependence fulfilling International Statistical Classification of Diseases, 10th Revision criteria of alcohol dependence. Audiovestibular function in this group was compared with social user of alcohol and complete abstainers.
Results: Statistically significant elevations of thresholds were found at higher frequencies (4000 and 8000 Hz ) in the alcohol-dependent group (P < .001). Alcohol-dependent patients had elevated thresholds at 4 and 8 kHz. Brainstem-evoked response audiometry showed prolongation of latencies of waves I, III, and V alone with interpeak latencies of I-III and III-V. One third of alcohol-dependent patients had abnormal electronystagmographic (ENG) findings. Abnormal ENG findings were only seen in alcohol-dependent patients with vertigo. There was no significant correlation between duration of alcohol dependence and abnormal ENG.
Conclusions: Elevated thresholds at higher frequencies can be the only abnormality in alcohol-dependent patients. Presence of vertigo in alcohol-dependent patient may be associated with abnormal ENG findings. There is no correlation of duration of dependence and ENG abnormalities.
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http://dx.doi.org/10.1016/j.amjoto.2005.09.005 | DOI Listing |
Clin Psychopharmacol Neurosci
February 2025
Department of Psychiatry, Korea University Guro Hospital, College of Medicine, Korea University, Seoul, Korea.
Objective: Prior research has emphasized psychological resilience as a potential protective factor against alcohol use disorder in diverse populations, with limited exploration of its relationship in the general population. This study investigated the association between the lifetime and one-year prevalence of alcohol use disorder and resilience.
Methods: Data obtained from the National Mental Health Survey of Korea 2021 (5,511 participants; 40.
BMC Public Health
January 2025
School of Psychology, Department of Educational, Social and Organizational Psychology, Makerere University, Kampala, Uganda.
Background: The HIV burden still persists to date, as a public global health challenge despite numerous prevention interventions that have been proposed toward achieving 95% of all people living with HIV aware of their HIV status by 2030. Therefore, this study set out to examine the effect of a workplace-based HIV self-testing intervention on the use of HIV self-testing among unskilled workers in Wakiso Uganda.
Methods: A quasi-experimental one-group pretest-posttest design was conducted among 46 participants systematically and randomly selected.
Addiction
January 2025
Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Background And Aims: Studies using smartphone apps in treatment for alcohol dependence are lacking. This study aimed to test the consumption-reducing effects of using two app-based alcohol interventions as complement to treatment as usual (TAU).
Design: Three-armed, parallel, randomised controlled trial.
Mol Psychiatry
January 2025
Icahn School of Medicine at Mount Sinai, Departments of Neuroscience, Psychiatry; Addiction Institute of Mount Sinai, New York, NY, USA.
Anxiety disorders are one of the top contributors to psychiatric burden worldwide. Recent years have seen a dramatic rise in the potential anxiolytic properties ascribed to cannabidiol (CBD), a non-intoxicating constituent of the Cannabis Sativa plant. This has led to several clinical trials underway to examine the therapeutic potential of CBD for anxiety disorders.
View Article and Find Full Text PDFPLoS One
January 2025
Laboratory of Hepato-Gastroenterology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
The emerging field of 3D organ modeling encounters several imaging issues in particular related to antigen retrieval and sample loss during staining processes. Due to their compact shape, several antibodies fail to penetrate intact organoids or spheroids. Histology of organoids can be approached by paraffin inclusion and sectioning at 5 μm as performed for biopsies.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!