The 4-amino-5-azaindole as an amidino-benzimidazole replacement is described. A series of potent and selective analogs were discovered and showed desirable ex vivo efficacy as measured by PT.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2006.06.016DOI Listing

Publication Analysis

Top Keywords

potent 4-amino-5-azaindole
4
4-amino-5-azaindole factor
4
factor viia
4
viia inhibitors
4
inhibitors 4-amino-5-azaindole
4
4-amino-5-azaindole amidino-benzimidazole
4
amidino-benzimidazole replacement
4
replacement described
4
described series
4
series potent
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!