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Although pseudoathetosis has been described in various conditions, it has been rarely reported in patients with epidural lesions. We report the first case of a patient with pseudoathetosis caused by a migrated cervical disc. The patient was a 76-year-old woman who presented with progressive clumsiness of the hands and athetotic movements. Electrophysiological studies revealed normal peripheral nerve conduction and delayed and attenuated cortical SEPs. Spinal MRI revealed an epidural mass with gadolinium enhancement at the C3-4 level. An anterior cervical surgery disclosed a migrated disc, and its removal resulted in a marked improvement. Migrated cervical disc should be considered in patients with a profound sensory loss and pseudoathetosis in the hands, because this condition is treatable.
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http://dx.doi.org/10.1016/j.parkreldis.2006.03.008 | DOI Listing |
Head Neck Pathol
March 2025
Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, University of the Western Cape and National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.
Background: Langerhans cell histiocytosis (LCH) rarely presents in the oral and maxillofacial region, and while isolated and small collections of Langerhans-type cells have been found in periapical cysts, there have been no reported cases of LCH arising in periapical cysts.
Methods: A 58-year-old female presented with isolated erythematous dry skin lesions and a radiolucent lesion of the anterior maxilla. Microscopic examination of the enucleation specimen revealed a periapical cyst with large collections of atypical cells with grooved folded nuclei with eosinophils consistent with LCH.
Hereditas
March 2025
Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, Fujian, China.
Background: Blood metabolites play an important role in predicting or influencing the occurrence and development of cancers. We aimed to evaluate the relationship between blood metabolites and the occurrence of head and neck cancer (HNC).
Methods: We employed a Mendelian randomization (MR) approach to investigate the role of blood metabolites in HNC predisposition.
Hereditas
March 2025
Department of Ultrasound, The First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road, Wuhua District, Kunming, Yunnan, 650032, China.
Background: Nasopharyngeal carcinoma (NPC) is a malignant head and neck cancer with high mortality and dismal prognosis. Emerging research have disclosed that circRNAs are crucial gene expression regulators engaged in tumor advancement. This work aspired to identify novel oncogenic circRNA driving NPC progression.
View Article and Find Full Text PDFSLAS Technol
March 2025
Department of Periodontics & Oral Mucosal Diseases, The Affiliated Stomatology Hospital, Southwest Medical University, Luzhou 646000, Sichuan, China; Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Luzhou 646000, Sichuan, China; Institute of Stomatology, Southwest Medical University, Luzhou 646000, Sichuan, China. Electronic address:
Background: Almost 90% of head and neck malignancies are malignant squamous cell cancers, making it the sixth most common malignancy in the developing countries, with an overall five-year overall survival rate about 40%-50%. Early diagnosis and treatment can bring a better prognosis. Fibroblast growth factor (FGF) is an important polypeptide in vivo.
View Article and Find Full Text PDFInt J Med Sci
March 2025
Department of Oncology, Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Fucosyltransferase 1 encodes a Golgi membrane protein involved in H-antigen precursor production and plays a critical role in tumor-associated glycosylation and angiogenesis. While FUT1 is known to enhance tumor stemness, adhesion, migration, and drug resistance in specific cancers, its role across diverse cancer types and its association with clinical prognosis and molecular features remain unclear. In this study, FUT1 expression was systematically analyzed across 33 cancer types using data from multiple public databases, including CCLE, TCGA, and GTEx.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!