Synthesis and anti-inflammatory activity of some selected aminothiophene analogs.

J Enzyme Inhib Med Chem

International Centerfor Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan.

Published: April 2006

Some 2-aminothiophene analogs 1-6 were synthesized and characterized. Among the tested compounds, compound 1 (IC50 121.47 microM) exhibited highest while the compound 5 showed least anti-inflammatory potential (IC50 422 microM).

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http://dx.doi.org/10.1080/14756360500480418DOI Listing

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