The goal of the work was to study behavior of rats in conditions of psychogenic stress on the background of ethanol intake. Experiments were carried out on 12 mature while rats weighing 150-200g. Before the beginning of the experiments during one month rats with high and low ethanol intake have been identified. Conditioned reflexes of active avoidance of the tone of 500 Hz and metronome knock using defensive method were elaborated in the next series of the experiments in the "stress box". At the same time behavioral characteristics (horizontal and vertical standings, intrasignal passages, grooming) were studied. It is interesting to note that in the process of separate elaboration of conditioned defensive reflexes as well as against the background of their "combination" much drinking rats became little drinking ones, and vice versa. General behavior of the animals also changed. A mean duration of horizontal standings intrasignal passages and grooming increased at the stages one and two, while they decrease at the stage three. As to vertical standings, their mean duration increased stage by stage. A mean duration of horizontal and vertical standings in little drinking rats decreased at the stages one and two, while dramatically increased at the stage three. All these behavioral reactions are considered to be self-regulating behavior, directed to the increase of organism resistance for the functioning of the brain in conditions of psychogenic stress.
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J Clin Med
January 2025
Department of Otolaryngology, Japan Community Healthcare Organization Tokyo Yamate Medical Center, Hyakunin-cho 3-22-1, Shinjuku-ku 169-0073, Tokyo, Japan.
: Dizziness and vertigo are reported in about half of patients with inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Orthostatic dysregulation (OD) is recognized as one of the comorbidities that causes dizziness or vertigo with IBD. Our hospital is affiliated with the Inflammatory Bowel Disease Center, which specializes in diagnosing and treating IBD, so cases with dizziness or vertigo symptoms associated with IBD are sometimes referred to our department, a type of department which is rare in other facilities.
View Article and Find Full Text PDFNeurol Int
January 2025
Department of Brain Repair & Rehabilitation, Institute of Neurology, University College London, London WC1E 6BT, UK.
The differential diagnosis of acute-onset amnesia includes transient global amnesia (TGA), transient epileptic amnesia (TEA), and functional (or psychogenic) amnesia. The most common of these, TGA, is a rare but well-described condition characterised by a self-limited episode of dense anterograde amnesia with variable retrograde amnesia. Although the clinical phenomenology of TGA is well described, its pathogenesis is not currently understood, thus preventing the development of evidence-based therapeutic recommendations.
View Article and Find Full Text PDFMult Scler Relat Disord
January 2025
Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy. Electronic address:
Background: There is increasing recognition Functional Neurological disorder (FND) is comorbid with other neurological conditions, but little is known about patients with Multiple Sclerosis (MS). We therefore systematically evaluated the presence of FND in consecutive patients with MS and its clinical correlates.
Methods: Three-hundred and ten consecutive MS patients, seen at our center on either elective or emergent basis, underwent a structured protocol to gather demographics and data about clinical features, previous and current treatments and presence of mood disorders and were additionally assessed by an expert in FND.
Ann Med
December 2025
Department of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Introduction: Psychogenic hearing loss is often neglected in the differential diagnosis of hearing disorders. In a difficult diagnostic process and treatment of psychogenic hearing loss disorder, the close cooperation of the audiologist, psychologist, patient, and his family is required. The study aimed to improve the knowledge and understanding of psychogenic hearing loss, establish a differential diagnosis in audiological tests in children, determine diagnostic procedures and finally apply adequate therapeutic procedures.
View Article and Find Full Text PDFPsychol Med
January 2025
MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Background: The mechanisms underlying generalized forms of dissociative ('psychogenic') amnesia are poorly understood. One theory suggests that memory retrieval is inhibited via prefrontal control. Findings from cognitive neuroscience offer a candidate mechanism for this proposed retrieval inhibition.
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