Multiple clinical informatics systems have been developed within separate departments of the University of Michigan Medical School. We are in the process of creating an "Honest Broker" method of safely and securely linking together data from different clinical systems for a research project studying the co-morbidity of depression and cardiovascular disease. The Michigan Clinical Research Collaboratory (MCRC) is an NIH/NHLBI Roadmap initiative funded to re-engineer the clinical research enterprise.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560785PMC

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