This study reports on the application of the knowledge discovery in database process to generate models that can predict the likelihood of falls among the elderly who reside in long-term care facilities. This process was applied to data held in the Minimum Data Set, a comprehensive resident assessment instrument being used in all Medicare and Medicaid supported nursing homes in the United States. For this study, we incorporated a new data mining technique, Likelihood Basis Pursuit, into the process. Using this technique, we were able to correctly identify which of the variables in this data set were associated with falls and generate models that could make fall likelihood predictions based upon those variables. Because the model provides probabilities based upon the exact combination of variables present in a particular resident, models constructed using this new data mining technique have the potential to be more useful for assessing fall risk.
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Int Orthop
January 2025
Stanford Medicine, Stanford, CA, USA.
Purpose: Subclinical peroneal neuropathy without overt foot drop has been linked to increased fall risk in adults, yet remains under reported due to subtle symptoms and lack of awareness. Patients with carpal tunnel syndrome (CTS) often experience other nerve entrapments, prompting this study to evaluate CTS (a proxy for peroneal nerve entrapment) as a significant predictor of time to first fall.
Methods: Data from the Merative MarketScan Research Databases (2007-2021) were used to identify adult patients using ICD-9/10 codes.
J Environ Manage
January 2025
Politecnico di Milano, Department of Civil and Environmental Engineering, Italy. Electronic address:
Stormwater runoff control is often a concern due to urbanization and extreme rainfall events. Sustainable urban drainage systems can support traditional hydraulic networks in rainwater management by providing local runoff disposal and reuse of collected stormwater. The objective of the study is based on an innovative analytical-probabilistic approach for evaluating the functioning of rainwater tanks in stormwater management with the potential for using collected water for non-potable purposes.
View Article and Find Full Text PDFAm J Med Genet B Neuropsychiatr Genet
January 2025
Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
BackgroundInsomnia is a common neurological disorder that exhibits connections with the gut microbiota; however, the exact causal relationship remains unclear. MethodsWe conducted a Mendelian randomization (MR) study to systematically evaluate the causal effects of genus-level gut microbiota on insomnia risk in individuals of European ancestry. Summary-level datasets on gut microbiota were sourced from the genome-wide association study (GWAS) of MiBioGen, while datasets on insomnia were obtained from the GWAS of Neale Lab and FinnGen.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Deparment of Developmental and Educational Psychology, University of Santiago de Compostela, Santiago de Compostela, Spain.
Background: The role of neuropsychiatric symptoms (NPS) as early markers of cognitive impairment progression along the cognitive impairment continuum needs further research. Our objective was to estimate to which extent NPS, measured with the Mild Behavioral Impairment Checklist (MBI-C), predict time-to-cognitive-worsening during follow-up in a sample of older adults recruited from primary care centers while controlling for other related variables (i.e.
View Article and Find Full Text PDFEur Geriatr Med
January 2025
Department of Biomedical and Neuromotor Science, Alma Mater Studiorum Università di Bologna, Ravenna Campus, Ravenna, Italy.
Purpose: Sarcopenia is a progressive and generalized skeletal muscle disorder, involving the accelerated loss of skeletal muscle mass and function, associated with an increased probability of adverse outcomes including falls. The circadian timing system may be involved in molecular pathways leading to sarcopenia in older adults. We aimed to provide an updated and systematic map of the available evidence on the role of the circadian timing system in sarcopenia, specifically related to the aging process.
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