Digital colour retinal photography is a useful modality for diabetic retinopathy screening. Unlike film photography, the size of the image depends on the resolution of the acquired image. With the availability of high-resolution digital cameras, larger images requiring greater storage-memory will inevitably be generated. Image compression may then be necessary so that these images can be viewed conveniently, archived and transmitted across computer networks. Unfortunately with the paucity of clinical studies on retinal image compression, more research is necessary to develop evaluation tools to identify optimum image compression ratios for diabetic retinopathy screening.
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http://dx.doi.org/10.1258/135763306777488799 | DOI Listing |
Ann Neurosci
January 2025
Department of Physiology, AIIMS, Bathinda, Punjab, India.
Background: Carpal Tunnel Syndrome (CTS) is the most common entrapment neuropathy, characterised by compression of the median nerve at the wrist. Traditional understanding views CTS as a distal compression issue, but recent evidence suggests potential proximal involvement.
Purpose: This study aimed to assess the prevalence of proximal median nerve conduction velocity (CV) slowing in CTS patients and examine its association with CTS severity.
APL Bioeng
March 2025
Blue Mountains World Interdisciplinary Innovation Institute (bmwi3), Blue Mountains, New South Wales, Australia.
Here, we report on the first part of a two-part experimental series to elucidate spatiotemporal cytoskeletal remodeling, which underpins the evolution of stem cell shape and fate, and the emergence of tissue structure and function. In Part I of these studies, we first develop protocols to stabilize microtubules exogenously using paclitaxel (PAX) in a standardized model murine embryonic stem cell line (C3H/10T1/2) to maximize comparability with previously published studies. We then probe native and microtubule-stabilized stem cells' capacity to adapt to volume changing stresses effected by seeding at increasing cell densities, which emulates local compression and tissue template formation during development.
View Article and Find Full Text PDFInt Wound J
January 2025
Division of Psychology and Mental Health, School of Health Sciences, University of Manchester, Manchester, UK.
Preventing recurrence of venous leg ulcers can be achieved through strongest tolerated compression and endo-venous ablation surgery, but it is not clear how often this is done in practice. This study explores (1) nurses' awareness of strongest tolerated compression and endo-venous ablation surgery as prophylactic treatments for venous leg ulcer, (2) how often these treatments are offered, and (3) assessment of the barriers and enablers to deploying those treatments using the capabilities, opportunities and motivations model of behaviour change. An online cross-sectional survey was conducted among nurses who treat and manage venous leg ulcers across the United Kingdom.
View Article and Find Full Text PDFInt Wound J
January 2025
Directorate of Nursing, Imperial College Healthcare NHS Trust/Imperial College London Education Centre, Charing Cross Hospital, London, UK.
Guidance for venous leg ulceration (VLU) recommends compression therapy and early referral for specialist vascular assessment within two weeks. Few patients receive timely assessment and referral. Reasons for this are unclear.
View Article and Find Full Text PDFBiomaterials
January 2025
Prometheus Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, PB 813, 3000, Leuven, Belgium; Skeletal Biology and Engineering Research, KU Leuven, ON1 Herestraat 49, PB 813, 3000, Leuven, Belgium. Electronic address:
Self-assembled cartilaginous microtissues provide a promising means of repairing challenging skeletal defects and connective tissues. However, despite their considerable promise in tissue engineering, the mechanical response of these engineered microtissues is not well understood. Here we examine the mechanical and viscoelastic response of progenitor cell aggregates formed from human primary periosteal cells and the resulting cartilaginous microtissues under large deformations as might be encountered in vivo.
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