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Two Novel Compounds Isolated from the Marine Fungal Symbiont of Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells: In vitro Study.
J Exp Pharmacol
January 2025
University Center of Excellence for Nutraceuticals, Bioscience and Biotechnology Research Center, Bandung Institute of Technology, Bandung, West Java, Indonesia.
Purpose: A promising feature of marine sponges is the potential anticancer efficacy of their secondary metabolites. The objective of this study was to explore the anticancer activities of compounds from the fungal symbiont of on breast cancer cells.
Methods: In the present research, , an endophytic fungal strain derived from the marine sponge was successfully isolated and characterized.
Electrochemical Monitoring of Vitamins B and C in Environmental Matrices with an Oligo Diaminotriazole Electrode.
ACS Omega
January 2025
Department of Physics, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Chemical polymerization/oligomerization opens numerous opportunities, from fundamental materials research to practical applications in catalysis, energy, sensing, and medicine. The electrochemical detection of vitamins B (folic acid) and C (ascorbic acid) requires new approaches because of low selectivity, electrode fouling, and interference from other chemicals. As an excellent material for long-term vitamin detection, oligo 3,5-diamino-1,2,4-triazole (oligo DAT) enhances the sensitivity, selectivity, and stability of sensors by creating a stable, conductive layer that facilitates electron transfer and reduces interference from common substances like glucose or uric acid.
View Article and Find Full Text PDFThe James Webb Space Telescope has discovered a surprising population of bright galaxies in the very early Universe (≲500 Myr after the Big Bang) that is hard to explain with conventional galaxy-formation models and whose physical properties are not fully understood. Insight into their internal physics is best captured through nebular lines, but at these early epochs, the brightest of these spectral features are redshifted into the mid-infrared and remain elusive. Using the mid-infrared instrument onboard the James Webb Space Telescope, here we present a detection of Hα and doubly ionized oxygen ([O iii] 4959,5007 Å) from the bright, ultra-high-redshift galaxy candidate GHZ2/GLASS-z12.
View Article and Find Full Text PDFFabrication of water-dispersible dye/polymer matrix-stabilized β-FeOOH (Rh-B/F127@β-FeOOH) nanoparticles: synthesis, characterization and therapeutic applications.
Nanoscale Adv
January 2025
Department of Mechanical Engineering, Yeungnam University Gyeongsan-si 38451 Gyeongbuk Republic of Korea
In this study, dye/polymer matrix-stabilized β-FeOOH nanomaterials were fabricated for therapeutic applications. Rh-B/F127@β-FeOOH nanomaterials were synthesized using two different methods: co-precipitation (CoP) and hydrothermal (HT) methods. The as-synthesized nanoparticles were characterized using various spectroscopic techniques, including FT-IR, UV-Vis, PL, XRD, HR-TEM, and XPS analysis.
View Article and Find Full Text PDFLinkage Microenvironment Modulation in Triazine-Based Covalent Organic Frameworks for Enhanced Photocatalytic Hydrogen Peroxide Production.
Small
January 2025
Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China.
Covalent organic frameworks (COFs), known for the precise tunability of molecular structures, hold significant promise for photocatalytic hydrogen peroxide (HO) production. Herein, by systematically altering the quinoline (QN) linkages in triazine (TA)-based COFs via the multi-component reactions, six R-QN-TA-COFs are synthesized with identical skeletons but different substituents. The fine-tuning of the optoelectronic properties and local microenvironment of COFs is allowed, thereby optimizing charge separation and improving interactions with dissolved oxygen.
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