[reaction: see text] 1,3-Diketones were synthesized directly from ketones and acid chlorides and were then converted in situ into pyrazoles by the addition of hydrazine. This method is extremely fast, general, and chemoselective, allowing for the synthesis of previously inaccessible pyrazoles and synthetically demanding pyrazole-containing fused rings.
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http://dx.doi.org/10.1021/ol060570p | DOI Listing |
Anal Methods
November 2017
Materials Science Centre, Indian Institute of Technology, Kharagpur-721302, India.
Functionalized polymer membrane electrodes based multichannel sensor is used as an electronic tongue to monitor the drinking water (DW) quality simply by measuring the surface electric potential with respect to Ag/AgCl reference electrode in 1 mM aqueous KCl. Changes of minute concentration of dissolved minerals greatly affected the surface potential of the sensor. The three-channel sensor device (electronic tongue) is made by using three different functionalized polymer membrane electrodes, namely, phosphorylated hexadecyl trimethyl ammonium chloride modified polyvinyl alcohol-polyacrylic acid membrane; phosphorylated and crosslinked polyvinyl--ethylene membrane; phosphorylated and crosslinked polyvinyl alcohol membrane, as working electrodes and a Ag/AgCl reference electrode.
View Article and Find Full Text PDFCrit Care
January 2025
Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Background: Low-volume hypertonic solutions, such as half-molar lactate (LAC), may be a potential treatment used for fluid resuscitation. This study aimed to evaluate the underlying cardiovascular effects and mechanisms of LAC infusion compared to sodium-matched hypertonic sodium chloride (SAL).
Methods: Eight healthy male participants were randomized in a controlled, single-blinded, crossover study.
Food Chem
January 2025
Department of Food Engineering and Technology, School of Food Engineering, State University of Campinas, Campinas, SP, Brazil. Electronic address:
Threshold determination forms an integral part of sensory and consumer studies applied for product control and development. The authors examined the potential of an impedimetric electronic tongue to discriminate basic tastes and consider limitations pertaining to the sensory evaluation process. Three samples at lower, medium, and higher concentration levels of basic taste compounds were prepared and subjected to consumer studies (n = 60) using the difference from-control (DFC) test.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Chemistry, State University of Maringá, Maringá, PR, Brazil; Laboratory of Materials, Macromolecules, and Composites, Federal University of Technology - Paraná, Apucarana, PR, Brazil; National Institute for Materials Advancement, Pittsburg State University, Pittsburg, KS, USA; Department of Chemistry, Pittsburg State University, Pittsburg, KS, USA. Electronic address:
Polyelectrolyte multilayers (PEMs) based on hyaluronic acid (HA) and poly (diallyldimethylammonium chloride) (PDDA) were deposited on oxidized polystyrene (PS) via the layer-by-layer (LbL) method. The X-ray photoelectron spectroscopy (XPS) confirmed the PEM deposition on PS, and atomic force microscopy (AFM) indicated that the surface roughness of PS also increased after PEM deposition. The PEMs significantly enhanced PS wettability, reducing the contact angle from 73° on PS to 24° on PDDA-terminated (PDDA/HA) PEM (2.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China; National Engineering Research Center for Fruit and Vegetable Processing, Key Lab of Fruit and Vegetable Processing, Ministry of Agriculture, Beijing, China.
This study utilized deep eutectic solvents (DES) based on choline chloride/lactic acid (ChCl/LA) to deconstruct coconut fibers. The effects of DES with different temperatures and molar ratios on the yield of lignin, recovery rate of residues, structural changes in lignin and solid residues, and saccharification efficiency were investigated. The results showed that acidic DES treatment effectively deconstructed the coconut fibers, resulting in a high lignin yield of 68.
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