We report a model of nanowire (NW) mechanics that describes force vs displacement curves over the entire elastic range for diverse wire systems. Due to the clamped-wire measurement configuration, the force response in the linear elastic regime can be linear or nonlinear, depending on the system and the wire displacement. For Au NWs the response is essentially linear since yielding occurs prior to the onset of the inherent nonlinearity, while for Si NWs the force response is highly nonlinear, followed by brittle fracture. Since the method describes the entire range of elastic deformation, it unequivocally identifies the yield points in both of these materials.
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Mater Horiz
January 2025
School of Materials Science and Engineering, Peking University, Beijing 1008711, P. R. China.
Intelligent soft robots that integrate both structural color and controllable actuation ability have attracted substantial attention for constructing biomimetic systems, biomedical devices, and soft robotics. However, simultaneously endowing single-layer cholesteric liquid crystal elastomer (CLCE) soft actuators with reversible 3D deformability and vivid structural color changes is still challenging. Herein, a multi-responsive (force, heat and light) single-layer 3D deformable soft actuator with vivid structural color-changing ability is realized through the reduced graphene oxide (RGO) deposition-induced Janus structure of the CLCE using a precisely-controlled evaporation method.
View Article and Find Full Text PDFFront Physiol
December 2024
Department of Health Sciences, Public University of Navarre (UPNA), Pamplona, Spain.
In this quasi-experimental before-after trial, we investigated the effects of a high-intensity, low-repetition inspiratory muscle training (HI-LRMT) protocol on respiratory muscle strength in instrumental musicians. In addition, was to estimate the prevalence of "non-responders" (NRs) in terms of muscle force after intervention. Healthy musicians ( = 48) were divided into 2 groups: HI-LRMT ( = 33) and a control group that did not train (CG, = 15).
View Article and Find Full Text PDFJ Cancer
January 2025
Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Breast cancer continues to be a significant global health challenge due to its heterogeneity and propensity for therapeutic resistance. The current tumor, node, and metastasis (TNM) staging and molecular classification systems are limited in capturing the full biological complexity of breast cancer. Myeloid differentiation primary response protein 88 (MyD88), a key adaptor protein in inflammatory signaling pathways, has been implicated in various oncogenic processes.
View Article and Find Full Text PDFFront Hum Neurosci
December 2024
Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
Introduction: The combination of magnetic and focused ultrasonic fields generates focused electric fields at depth entirely noninvasively. This noninvasive method may find particularly important applications in targeted treatments of the deep brain circuits involved in mental and neurological disorders. Due to the novelty of this method, it is nonetheless unknown which parameters modulate neural activity effectively.
View Article and Find Full Text PDFNature
January 2025
Department of Mechanical Engineering, Columbia University, New York, NY, USA.
Mechanical force is an essential feature for many physical and biological processes, and remote measurement of mechanical signals with high sensitivity and spatial resolution is needed for diverse applications, including robotics, biophysics, energy storage and medicine. Nanoscale luminescent force sensors excel at measuring piconewton forces, whereas larger sensors have proven powerful in probing micronewton forces. However, large gaps remain in the force magnitudes that can be probed remotely from subsurface or interfacial sites, and no individual, non-invasive sensor is capable of measuring over the large dynamic range needed to understand many systems.
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