AI Article Synopsis
- Repeated intramuscular injections of a low molecular weight heparin-collagen complex enhanced the breakdown of blood clots (fibrinolytic activity) and reduced the clumping of platelets in rats with a depressed anticoagulant system.
- The study lasted for 11 months and focused on the effects of this treatment on the rats' blood properties.
- When these rats were given a substance called alloxan, which typically induces diabetes, they did not develop diabetes mellitus.
Article Abstract
Repeated intramuscular administration of low molecular weight heparin-collagen complex proved to increase fibrinolytic activity and to decrease platelet aggregation in the blood of rats (11 months) with depressed anticoagulant system. Administration of diabetogenic alloxan dose induced no diabetes mellitus in such animals.
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