In this article, we present key lessons that we have learned from (1) a long program of research on an empirically supported treatment, brief strategic family therapy (BSFT), and (2) our ongoing research and training efforts related to transporting BSFT to the front lines of practice. After briefly presenting the rationale for working with the family when addressing behavior problems and substance abuse in adolescent populations, particularly among Hispanic adolescents, we summarize key findings from our 30-year program of research. The article closes by identifying barriers to the widespread adoption of empirically supported treatments and by presenting current work within the National Institute on Drug Abuse's Clinical Trials Network that attempts to address these barriers and obstacles.
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http://dx.doi.org/10.1111/j.1545-5300.2006.00094.x | DOI Listing |
FASEB J
March 2025
Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Cancer and cardiovascular disease remain the leading causes of morbidity and mortality worldwide, and the two separate disease entities share several similarities and possible interactions. Patients with cancer may have underlying cardiovascular disease, which is often exacerbated by the stress of tumor growth or treatment. At the same time, cardiotoxicity induced by anti-cancer therapies or the malignant process itself can lead to new cardiovascular diseases.
View Article and Find Full Text PDFPLoS One
March 2025
Discipline of Pharmaceutical Sciences, School of Health Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South Africa.
Introduction: There is an ongoing global upsurge of opioid misuse, fatal overdose and other related disorders, significantly affecting the African continent, due to resource-limited settings and poor epidemiological surveillance systems. This scoping review maps scientific evidence on epidemiological data on unlawful opioid use to identify knowledge gaps and policy shortcomings.
Method: The databases (PubMed, Scopus, Web of Sciences) and references were searched guided by Population, Concept, and Context (PCC) and PRISMA-ScR.
Mol Psychiatry
March 2025
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Introduction: Neuroinflammation is associated with both early and late stages of the pathophysiology of Alzheimer's disease (AD). Fluid biomarkers are gaining significance in clinical practice for diagnosis in presymptomatic stages, monitoring, and disease prognosis. This systematic literature review (SLR) aimed to identify fluid biomarkers for neuroinflammation related to clinical stages across the AD continuum and examined long-term outcomes associated with changes in biomarkers.
View Article and Find Full Text PDFInt J Biol Macromol
March 2025
Department of General Surgery, the Second Affiliated Hospital of Army Medical University, Chongqing, China. Electronic address:
Keratins, as essential components of intermediate filaments in epithelial cells, play a crucial role in maintaining cell structure and function. In various malignant epithelial tumors, abnormal keratin expression is frequently observed and serves not only as a diagnostic marker but also closely correlates with tumor progression. Extensive research has demonstrated that keratins are pivotal in multiple stages of tumor metastasis, including responding to mechanical forces, evading the immune system, reprogramming metabolism, promoting angiogenesis, and resisting apoptosis.
View Article and Find Full Text PDFHealth Justice
March 2025
The Institute for Family Health, King Hussein Foundation, Amman, 11910, Jordan.
Background: Existing evidence elucidates the psychological dimensions of juvenile delinquency, yet the need for cross-cultural validation remains critical to deepen and diversify our understanding of delinquency across different settings. Properly assessing and addressing the mental health needs of youth involved in the justice system (YIJS) is a strategic step that can help design and implement comprehensive responses to produce healthier youth who are less likely to act out and commit crimes. To this aim, this study explored several key mental health dimensions among YIJS who were incarcerated in rehabilitation centers located in Jordan.
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