In 1947, Paul Beeson showed that rabbits repeatedly injected with certain bacteria eventually become resistant to the bacteria's fever-provoking effects-a phenomenon known as endotoxin tolerance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121195 | PMC |
| http://dx.doi.org/10.1084/jem.2035fta | DOI Listing |
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