Purpose: To develop a new method using binocular rivalry and retinometers to quantitatively examine ocular dominance and to investigate the magnitude of ocular dominance in cataract patients preoperatively and postoperatively.
Setting: Eye Clinic, Kitasato University School of Medicine Hospital, Sagamihara, Kanagawa, Japan.
Methods: The duration of exclusive visibility of the dominant and nondominant eye target in binocular rivalry were measured in 60 healthy volunteers (study 1) and preoperatively and postoperatively in 10 cataract patients (study 2). Rivalry targets were presented directly to the retina of each eye using 2 retinometers. Subjects reported the exclusive visibility of 1 eye target, and the total duration of exclusive visibility for each eye in dominant and nondominant eye trials was evaluated.
Results: In study 1, the magnitude of ocular dominance was quantitatively assessed with 4 grades based on differences in total duration of exclusive visibility between dominant and nondominant eyes. In study 2, magnitude of ocular dominance could be evaluated in all cataract patients regardless of refractive and cataract conditions. Magnitude of ocular dominance displayed significant correlations between preoperative and postoperative conditions (simple regression, P<.001).
Conclusions: Ocular dominance can be quantitatively evaluated using this new method based on binocular rivalry and retinometers, particularly in cataract patients. Magnitude of ocular dominance may indicate preoperatively whether a patient with cataracts will have sufficient ocular dominance to adjust to monovision correction.
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http://dx.doi.org/10.1016/j.jcrs.2006.01.082 | DOI Listing |
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.
Purpose: Eyelid infiltrative basal cell carcinoma (iBCC) is the most common malignant tumor affecting the ocular adnexa, but studies on metabolic changes within its microenvironment and heterogeneity at the tumor invasive area are limited. This study aims to analyze metabolic differences among iBCC cell types using single-cell and spatial metabolomics analysis and to examine metabolic environment at the tumor invasive area.
Methods: Single-cell transcriptomic data of human basal cell carcinoma (BCC) were clustered and visualized using Uniform Manifold Approximation and Projection.
J Clin Med
December 2024
Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
: Ocular proprioception is implicated in balance control and heterophoria is associated with abnormal posture, though previous research focused mainly on the role of vertical phoria and the use of vertical prisms. This study aims to evaluate whether ocular misalignment and prismatic correction of horizontal phoria affect posture. : Sixty-nine ( = 69) young healthy subjects were included and equally divided by horizontal distance phoria: orthophoria ( = 23), esophoria ( = 23) and exophoria ( = 23).
View Article and Find Full Text PDFDoc Ophthalmol
December 2024
Department of Ophthalmology, Bilkent City Hospital, Ankara, Turkey.
Purpose: The aim of this study was to compare retinal and optic disc functions as well as vascular structures in dominant eyes (DE) and non-dominant eyes (NDE) among healthy adults using pattern electroretinogram (PERG), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) tests.
Methods: Seventy-two eyes of 36 healthy subjects with bilateral visual acuity of 1.0 were included.
Ophthalmic Plast Reconstr Surg
December 2024
Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.
Purpose: To characterize symptoms and signs for patients with tearing eye(s) and ipsilateral nasolacrimal duct stenosis (NLDS), as defined by delayed fluorescein disappearance test and ocular reflux of saline during gentle irrigation of a patent drainage system.
Methods: Retrospective case-note review of a consistent grading of 4 symptoms and 7 signs, together with estimates of the degree of fluid reflux and nasal fluid passage on gentle saline syringing. Characteristics, including gender differences, were compared for unilateral or bilateral symptoms.
iScience
December 2024
Department of Molecular Visual Plasticity, Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands.
Endocannabinoids, signaling through the cannabinoid CB1 receptor (CB1R), regulate several forms of neuronal plasticity. CB1Rs in the developing primary visual cortex (V1) play a key role in the maturation of inhibitory circuits. Although CB1Rs were originally thought to reside mainly on presynaptic axon terminals, several studies have highlighted an unexpected role for astrocytic CB1Rs in endocannabinoid mediated plasticity.
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