[New perspectives in the diagnosis and evolution of the consumption of tobacco: markers of susceptibility and damage].

The smoking represents a serious problem of public health. It is in and of itself high-priority to describe the genetic bases of the addiction, the susceptibility to begin the consumption, to be smoking and to develop pathologies related with the tobacco. Markers of susceptibility (I begin, consolidation, modulation and ceasing of the habit), of damage potential -chronic obstructive pulmonary disease (COPD), lung carcinoma-, and of valuation of the adverse goods of the exhibition. Dependence markers, motivation, depression, anxiety and stress are reviewed. As well as tests to value syndrome of abstinence, breathing analytic and functional parameters and quality of life.