We evaluated the performance characteristics of a new, real-time nucleic acid sequence-based amplification (NASBA) assay that incorporates molecular beacon technology for detection of human immunodeficiency virus type 1 (HIV-1). The quantitative results were comparable to those obtained with three leading commercially available assays. The analytical sensitivity was 37 IU/ml. The NASBA assay detected clinically relevant recombinant viruses and all group M HIV-1 subtypes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489398 | PMC |
| http://dx.doi.org/10.1128/JCM.02187-05 | DOI Listing |
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