AI Article Synopsis
- The phylogenetic analysis determined that previously nontypeable hepatitis C virus isolates from Argentina are identified as genotype 1a.
- A specific genetic substitution (G-->A at position 107) is characteristic of these strains and appears in similar isolates globally.
- The RFLP patterns from these Argentine isolates should be incorporated into the existing database of genotype 1 patterns.
Article Abstract
Phylogenetic analysis of hepatitis C virus isolates from Argentina that were previously nontypeable by restriction fragment length polymorphism (RFLP) analysis revealed that they belong to genotype 1a. A substitution at position 107 (G-->A), which is the landmark of these strains, was shown to be distributed among isolates worldwide. The RFLP patterns obtained for these isolates should be added to the ones reported for genotype 1 isolates.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489453 | PMC |
| http://dx.doi.org/10.1128/JCM.02569-05 | DOI Listing |
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