A case of skin necrosis as a result of cholesterol crystal embolisation.

J Plast Reconstr Aesthet Surg

Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Marmara University, Tophanelioglu Caddesi, Altunizade, Uskudar, Istanbul, Turkey.

Published: June 2006

AI Article Synopsis

  • - Cholesterol crystal embolism is a serious multisystem condition often occurring after vascular surgery or prolonged anticoagulation therapy, yet it's frequently misdiagnosed.
  • - Early recognition of skin symptoms, like livedo reticularis and skin necrosis, is crucial for timely diagnosis and treatment to prevent complications.
  • - A case study highlights a patient who developed acute renal failure and skin issues post-angioplasty, where a biopsy confirmed cholesterol crystals; he received wound care and surgery for tissue repair, resulting in full healing after one month.

Article Abstract

Cholesterol crystal embolism is a multisystem disorder with a high mortality. It is usually seen following vascular surgery and long term anticoagulation therapy, but the diagnosis is often not considered. Skin manifestations are the first sign of cholesterol crystal embolism and recognition of the symptoms is a key element in early diagnosis and prevention of recurrences. We report a case who presented with acute renal failure, livedo reticularis and skin necrosis following angioplasty. Cutaneous biopsy revealed cholesterol crystals in the lumen of a vessel. Necrotic sites were treated with daily wound care and he was operated for reconstruction of tissue defects with cutaneous advancement flaps. One month after the operation healing was complete.

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http://dx.doi.org/10.1016/j.bjps.2005.09.033DOI Listing

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