The aim of investigation was to study the morphologic features and morphometric parameters of coronary sinus of the human heart with special reference to age- and gender-dependent differences. 330 hearts of male and female patients, who died at the age of 21-92 years from different reasons, were in studied. The length and width of coronary sinus and its main shape characteristics were analyzed. 57 histological specimens were stained with hematoxylin-eosin, using van-Gieson's and Hart's method. The coronary sinus tunics were described and their thickness was measured. As the result of this study, it was found that both length and width of coronary sinus at the point of its entrance into the right atrium were dependent on the gender of the patients and were larger in males. The width of coronary sinus increased with age in the patients with diseases characterized by predominant loading of the left ventricle. In these patients, conical shape of coronary sinus was present in all the ages. In humans with no diseases of cardiovascular system, the shape of coronary sinus was shown to change with age from cylindrical to conical. The thickness of tunics forming the walls of coronary sinus in this group was independent on gender and age.
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