The phytochemical study of the aerial parts of Viburnum chinshanense Graebn., a species growing in Western and Central China, led to the isolation of six iridoid glucosides: the novel 10,2'-diacetylpatrinoside, 1, and the known 2'-acetyldihydropenstemide, 2'-trans- p-coumaroyl-dihydropenstemide, 2'-acetylpatrinoside, decapetaloside, and patrinoside. In addition, amentoflavone and rosarin were also isolated.
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http://dx.doi.org/10.1080/14786410500056678 | DOI Listing |
J Chromatogr Sci
January 2025
Characteristic Biology Resources Research Center, Northwest Institute of Plateau Biology, Chinese Academy of Science, No. 23, Xinning Road, Chengxi District, Xining, Qinghai 810001, P. R. China.
Separation of polar compounds especially with similar polarities is challenging. In the present study, three polar compounds with similar polarities, including gentiopicroside, sweroside and mangiferin, have been successfully separated from Swertia mussotii by a combination of two counter-current chromatography modes. With the selected solvent system of ethyl acetate/n-butanol/water (8/2/10, v/v), a continuous injection mode was firstly employed.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Clinical Pharmacy, Baoshan Hospital Affiliated to, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
This study investigates the potential treatment of breast cancer utilizing Gentiana robusta King ex Hook. f. (QJ) through an integrated approach involving network pharmacology, molecular docking, and molecular dynamics simulation.
View Article and Find Full Text PDFMol Biol Rep
December 2024
Department of Physiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Background: Oleuropein (OLE) has the potential to reduce oxidative stress and inflammation. So, in the present investigation, we explored the protective effect of OLE on brain aging induced by d-galactose (D-Gal) in a rat model.
Methods And Results: 40 Wister male adult rats were categorized into 5 groups.
Zhongguo Zhong Yao Za Zhi
November 2024
Wangjing Hospital of China Academy of Chinese Medical Sciences Beijing 100102, China Beijing Key Laboratory of Orthopaedic Technology of Traditional Chinese Medicine Beijing 100102, China.
This study aimed to investigate the effect of aucubin(AU) on injury of nucleus pulposus cells and extracellular matrix(ECM) degradation and its mechanism. The nucleus pulposus cell injury model was established by interleukin-1β(IL-1β) and treated with AU or phosphatidylinositol 3-kinase(PI3K) inhibitor LY294002. CCK-8 experiment was conducted to test cell proliferation.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China.
The hairy roots of (Gaertn.) Libosch. ex Fisch.
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